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KMID : 0370920060230020232
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Yeungnam Univercity Journal of Medicine
2006 Volume.23 No. 2 p.232 ~ p.239
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Two Cases of Alopecia Totalis Treated with Diphenylcyclopropenone(DPCP) Immunotherapy
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Moon Seok-Ki
Shin Young-Min
Shin Dong-Hoon
Choi Jong-Soo
Kim Ki-Hong
Kim Chan-Woo
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Abstract
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Treatments for alopecia areata include topical corticosteroid treatment, corticosteroid intralesional injection, systemic corticosteroid treatment, PUVA(psoralen-UVA) and topical immunotherapy. The therapeutic effects are variable. Alopecia totalis is hard to treat completely. Topical immunotherapy with dinitrochlorobenzene (DNCB), squaric acid dibutyl ester (SADBE) or diphenylcyclopropenone (diphencyprone, DPCP) represents the most accepted therapeutic modality for the treatment of extensive alopecia areata. We report two cases of alopecia totalis treated with DPCP. After DPCP treatment, total scalp hair was completely recovered.
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KEYWORD
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Diphenylcyclopropenone(DPCP), Alopecia totalis, Alopecia areata
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